The traditional drug discovery and development mainly focuses on directly regulating the activity of proteins or enzymes to treat diseases, mainly through the pharmacological mode of occupancy-driven to control the function of proteins. It is estimated that only 10% of proteins can be regulated by small molecules, and 10% of proteins that can be regulated by biological macromolecules are on the cell surface. And up to 80% of the proteins can't be regulated by existing drugs. Therefore, PROTAC is emerging as a promising technique in the development of therapeutics.
As a leading service provider in drug discovery and development, BOC Sciences is fully qualified and committed to providing one-stop PROTAC® development, which has become a promising strategy in the field of small molecular drug discovery. With a comprehensive and advanced platform, we provide Ligand Design for Target Protein to customers around the world to meet new drug discovery goals.