Creative BioMart provides modulators and inhibitors for proteins and enzymes involved in DNA / histone demethylation. We can proudly guarantee that our small-molecule products are of high quality and high purity and are your ideal tool for studying epigenetic regulation mechanisms and epigenetic drug screening.
The process of removing methyl groups from histones by histone demethylases (HDMs) is defined as histone demethylation, which affects chromatin inactivation and gene expression. There are two main classes of HDMs: 1) flavin-adenine dinucleotide (FAD)-dependent family of amine oxidase; 2) Fe (II) and α-ketoglutarate-dependent hydroxylase. Modulators and inhibitors of HDMs can also be classified according to their specificity for different types of demethylases. Histone demethylation inhibitors inhibit HDM and provide information on diseases associated with histone demethylation, such as cancer.