Online Inquiry >
Membrane proteins play a vital role in many biological processes, and nearly 30% of proteins in eukaryotic cells are known to be membrane proteins. They have proven to be difficult to study due to their partially hydrophobic surfaces and lack of stability outside the lipid bilayer environment that is critical for membrane protein structure and activity. Crystallization of these proteins is notoriously challenging, which usually involves extensive detergent screening to identify optimal conditions.
https://www.creative-biostructure.com/membrane-protein-crystallization-549.htm
