Description: The picture represents a 3D-reconstruction (using Imaris software) of confocal/multiphoton (Leica SP5) images collected through the thickness (100 micrometers) of a live lymph node from a bone-marrow transplanted mouse. Cells marked by five fluorescent proteins: Cerulean (cyan), EGFP (green), Venus (yellow), tdTomato (purple), mCherry (red) appear surrounded by collagen matrix (second harmonic generation-SHG, white) at 4 months post-transplant. Authors: Daniela Malide, Jean-Yves Metais, and Cynthia Dunbar Licensing: Attribution Non-Commercial No Derivatives: This image is licensed under a Creative Commons Attribution, Non-Commercial, No Derivatives License