Huge tumor of the neck: where does it orignate?
Findings from the biopsy sample: extensive neurotic parts of a pleomorphic malignant neoplasm (undifferentiated). Reactivated for CD56 as sign of a neuroendocrine differentiation and Pax-8 positive as hint for an origin in the thyroid. Proliferative index Ki67 very high, which was to be expected. Stain for CEA, GATA3, chromogranin, synaptosin and calcitonin negative. Stain for thyreoglobulin slightly positive.
CT 2, 3, 4, 5, 6, 7. 8. 9. 10, 11
Patient 1, 2, 3